中国临床肿瘤学会（CSCO）白血病专家委员会、淋巴瘤专家委员会及骨髓瘤筹备委员会工作会议暨2024年CSCO血液及淋巴瘤、骨髓瘤疾病学术大会

柳燕简介
柳燕：女，2014年 6月安徽省教育厅、安徽医科大学海外(University of Texas Medical Branch)高层次引进人才，教授，硕士生导师。三类人才。
2007-2014 年在美国 University of Texas medical Branch 大学病理系作为访问科学家、III 级副研究员、研究员以及实验室负责人管理实验室科研活动和实验指导。主要从事新布尼亚病毒致病机理、立克次体类疾病致病机理及疫苗研究。
主要研究方向是蜱、螨传播的新发、再发自然疫源性疾病病原及致病机理研究，主要包括发热板血小板减少综合症病毒、斑点热立克次体及恙虫病病原体。
 
一、2014年入职安徽医科大学以来所获得的科研课题

1. 在研主持国家自然科学基金面上项目“我国新分离斑点热立克次体主要表面蛋白对THP-1细胞专嗜性的致病机制研究”,项目号：81571963，直接经费55万，时间：2016.01~2019.12。二类

2. 在研主持国家自然科学基金面上项目“脾脏FRCs在新布尼亚病毒致死性感染中自噬机制研究” ，项目号：81772203，直接经费53万，时间：2018.01~2021.12。二类

3. 在研主持安徽省科技厅自然科学基金项目面上项目“OmpB及氨基酸突变的其它表面暴露蛋白在我国新发现斑点热立克次体致病机理的研究”。项目号：1608085MH213，项目经费8万。三类

4. 主持安徽省教育厅重点项目“安徽省新发现日本斑点热立克次体疫源地研究”。项目编号：KJ2015A020，项目经费6万。三类

5. 安徽医科大学博时启动资金。项目号：XJ201430，项目经费30万。

 
 
 
二、获省部级科技奖：
1. 获2016年安徽省科学技术奖二等奖，获奖题目《新发传染病发热伴血小板减少综合症病原、流行特征及致病机理》，第一获奖人，获奖编号：2016-2-R1。二类
2. 获2009年中国卫生部预防医学会科技进步二等奖，获奖题目《中国无形体病的发现》，第七获奖人，获奖编号：20090124-2-G1007。二类
3. 1987年，因“家猫作为流行性出血热传播的意义研究及探讨”的研究，作为项目主要完成人获安徽省科技进步二等奖，证书号：87—2—107。二类
 
三、已发表SCI论文：

1. Latif A, Liu B-Y, Chen Z, Sun Y, Shi Y-L, Zong J, Li -J, Ren C-P, Zhang X-C, Liu X-N, Yuc X-J, Liu Y. Orientia tsutsugamushi infection in rodents in Anhui Province of Chin. Infection, Genetics and Evolution.  2017.56:14-18. IF:2.88.

2. Liu Y, Yu X-J. Identification and Diagnosis of Newly Emerging Pathogens.  Infectious Diseases and Translational Medicine. 2017.

3. Liu Y, Yu X-J. Human granulocytic anaplasmosis and Lyme disease–reply. JAMA. 2016;316:99. ttp://dx.doi.org/10.1001/jama.2016.4295. IF: 37. Cited by 2, as of Nov, 2017

4. Liu Y, Wu B , Weinstock G , Walker DH , Yu XJ.  Inactivation of SAM-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain. Plos One. 2014, in press. IF:3.7. Cited by 3, as of Nov, 2017

5. Liu Y, Wu B, Paessler S, Walker DH, Tesh RB, Yu XJ. The pathogenesis of SFTSV infection in IFNα/β knockout mice: insights into the pathologic mechanisms of a new viral hemorrhagic fever. J Virol. 2014, 88:1781-1786. IF:5.07. Cited by 23, as of Nov, 2017

6. Liu Y, Li Q, Hu W, Wu J, Wang Y, Mei L, Walker DH, Ren J, Wang Y, Yu XJ. Person-to-Person Transmission of Severe Fever with Thrombocytopenia Syndrome Virus. Vector Borne Zoonotic Dis. 12:156-60, 2012. PubMed PMID: 21955213. IF: 2.80. Cited by 162, as of Nov, 2017

7. Yu XJ^§, Liang MF^§, Zhang SY^§, Liu Y^§, Li JD^§, Sun YL^§, Zhang L, Zhang QF, Popov VL,Li C, Qu J, Li Q, Zhang YP, Hai R, Wu W, Wang Q, Zhan FX, Wang XJ, Kan B, Wang SW, Wan KL, Jing HQ, Lu JX, Yin WW, Zhou H, Guan XH, Liu JF, Bi ZQ, Liu GH, Ren J, Wang H, Zhao Z, Song JD, He JR, Wan T, Zhang JS, Fu XP, Sun LN, Dong XP, Feng ZJ, Yang WZ, Hong T, Zhang Y, Walker DH, Wang Y, Li DX. Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med. 21;364(16):1523-32, 2011. PMCID: PMC3113718. (I was a co-first author). IF: 55. Cited by 829, as of Nov, 2017

8. Liu Y, Zhang Z, Jiang Y, Zhang L, Popov VL, Zhang J, Walker DH, Yu XJ. Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity. Microbes Infect. 2011 Mar;13(3):232-8. IF: 2.92. Cited by 26, as of Nov, 2017

9. Liu Y，Gao R, Hu W, Ma M, Wang W, He J, Wang J, Li D, Shu Y. Detection of Highly Pathogenic Avian Influenza Virus H5N1 in Peripheral Blood Mononuclear Cells and Stool of a Patient. Labmedicine. 42(5): 310-313. 2011. Cited by 1, as of Nov, 2017

10.  Zhang S^§, Song H^§, Liu Y^§, Wang Y, Wu J, Wan J, Li G, Yu C, Li X, Li Q, Yin W, Xu Z, Liu B, Zhang Q, Wan K, Li G, Fu X, Zhang J, He J, Hai R, Yu D,. Walker DH, Xu J, Yu XJ. Scrub Typhus in Previously Unrecognized Areas of Endemicity in China. J. Clin. Microbiol. 48: 1241-4, 2010. (co-first author). IF: 4.06. Cited by 59, as of Nov, 2017

11. Zhang L^§, Liu Y^§, Ni D^§, Li Q^§, Yu Y^§, Yu XJ^§, Wan K, Li D, Liang G, Jiang X, Jing H, Run J, Luan M, Fu X, Zhang J Yang W, Wang Y, Dumler JS, Feng Z, Ren J, and Xu J. Nosocomial transmission of human granulocytic anaplasmosis in China. JAMA, 300:2263 – 2270, 2008. (co-first author). IF: 37. Cited by 226, as of Nov, 2017

12. Latif A, Liu B-Y, Chen Z, Sun Y, Shi Y-L, Zong J, Li -J, Ren C-P, Zhang X-C, Liu X-N, Yuc X-J, Liu Y. Orientia tsutsugamushi infection in rodents in Anhui Province of Chin。Infection, Genetics and Evolution. Online 2017.10.12. IF:2.88.

13. Cheng Y, Liu Y, Bin W, Zhang JZ, Gu J, Liao YL, Wang FK, Mao XH, Yu XJ. Proteomic analysis of the Ehrlichia chaffeensis phagosome in cultured DH82 cells. Plos One. 10.1371/journal.pone.0088461. 2014. IF:3.7. Cited by 9, as of Nov, 2017

14. Wen HL, Zhao L, Zhai S, Chi Y, Cui F, Wang D, Wang L, Wang Z, Wang Q, Zhang S, Liu Y, Yu H, Yu XJ. Severe fever with thrombocytopenia syndrome, Shandong Province, China, 2011. Emerg Infect Dis. 20: 1-5, 2014. IF:7.3. Cited by 22, as of Nov, 2017

15. Zhang, X, Liu Y, Zhao, L, Li B, Yu H, Wen H, Yu XJ. An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV. Science China Life Sciences, 56, 697-700, 2013. IF: 2.02. Cited by 45, as of Nov, 2017

16. Gong B, Ma L, Liu Y, Gong Q, Shelite T, Bouyer D, Boor PJ, Lee YS, Oberhauser A. Rickettsiae induce microvascular hyperpermeability via phosphorylation of VE-cadherins: evidence from atomic force microscopy and biochemical studies. PLoS Negl Trop Dis. 2012;6(6):e1699. doi: 10.1371/journal.pntd.0001699. IF: 4.56. Cited by 11, as of Nov, 2017

17. Zhang S^§, Song H^§, Liu Y^§, Wang Y, Wu J, Wan J, Li G, Yu C, Li X, Li Q, Yin W, Xu Z, Liu B, Zhang Q, Wan K, Li G, Fu X, Zhang J, He J, Hai R, Yu D,. Walker DH, Xu J, Yu XJ. Scrub Typhus in Previously Unrecognized Areas of Endemicity in China. J. Clin. Microbiol. 48: 1241-4, 2010. (I was a co-first author). IF: 4.06. Cited by 59, as of Nov, 2017

18. Driskell LO, Yu XJ, Zhang L, Liu Y, Popov VL, Walker DH, and Wood DO. Directed mutagenesis of the Rickettsia prowazekii pldgene encoding phospholipase D.  Infect and Immun, 77:3244-8, 2009. IF: 4.07. Cited by 61, as of Nov, 2017

19. Yu XJ, Walker DH, Liu Y, and Zhang LH.  Amino acid biosynthesis deficiency in bacteria associated with human and animal hosts. Infect Genet Evol, 9:514-7, 2009. IF: 2.76. Cited by 9, as of Nov, 2017

20. Zou S, Han J, Wen L, Liu Y, Cronin K, Lum SH, Gao L, Dong J, Zhang Y, Guo Y,Shu Y. Human influenza A virus (H5N1) detection by a novel multiplex PCR typing method. J Clin Microbiol. 2007 Jun;45(6):1889-92. IF: 4.06. Cited by 53, as of Nov, 2017

 
四、SCI杂志审稿人 以下四种国外杂志审稿

1. Vector-Borne and Zoonotic Diseases

2. American Journal of Tropical Medicine and Hygiene 

3. Enzyme and Microbial Technology

4. PLos ONE

 
五、学术任职：

1. 中华医学会病毒学分会现任委员

2. 中华医学会热带病与寄生虫病学分会虫媒传染病学组委员

3. 中国微生物学会人兽共患病病原学专业委员会现任委员，兼立克次体（含埃立克体、无形体）学组副组长

4. 中华医学会安徽分会微生物与免疫学分会现任主任委员

5. 中华医学会安徽分会热带病与寄生虫病学现任常委